pMEV2HA-OCT3/4

Human OCT3/4 Xpress Clone Human POU class 5 homeobox 1 (POU5F1)Genes such as OCT3/4, SOX2, NANOG, LIN28 and KLF4 are highly expressed in undifferentiated embryonic stem cells and progenitor cells. They are important for stem cells to have their special properties or "stemness", and hence are sometimes called "Stemness Genes". Tremendous advances have been achieved recently in induced pluripotent stem (iPS) cells from mouse and human somatic cells. These cells have enormous potentials in curing many human diseases. To facilitate stem cell research and exploration, we offer all the "Stemness Genes" that have been used to induce iPS: OCT3/4, SOX2, NANOG, LIN28, c-Myc and KLF4.OCT3/4, SOX2, c-Myc and KLF4 were initially used to generate induced pluripotent stem cells (iPSC) from mouse adult cells. Human somatic cells were later induced with the same set of genes, and with a different set of genes consisting OCT3/4, SOX2, NANOG and LIN28. - 20 ug